10 Differences between LDL and HDL !

Before knowing about differences between HDL and LDL, let us know, What is Cholesterol?

  • Cholesterol is the fat like substance present in our body.
  • Cholesterol is important in making cell membranes, hormones, Vitamin D etc.
  • Cholesterol are also necessary to produce bile acids, which help the body digest fat and absorb important nutrients.
  • Liver and intestine produce 80% of cholesterol and remaining 20% is obtained from food
  • As cholesterol cannot mix with water and cannot move freely in the blood, it gets attached to the protein, making a complex called lipoproteins. Lipoproteins are made up of fats and proteins. There are two main forms of lipoprotein; -LDL and HDL

Some major differences between LDL and HDL are:

                    LDL

                         HDL

LDL stands for Low Density Lipoprotein HDL stands for High Density Lipoprotein
Also known as BAD CHOLESTEROL, because it transports cholesterol to our arteries, where it may accumulate in the artery walls Also known as GOOD CHOLESTEROL, because it transports cholesterol to our liver so that the cholesterol can be expelled out from the body
Size is 18- 25 nm Size is 5- 12 nm
Approximately 50 percent of the weight of an LDL particle is cholesterol and only 25 percent is protein High-density lipoprotein particles, on the other hand, consist of 20 percent cholesterol by weight and 50 percent protein
Low-density lipoproteins contain proteins called B-100 proteins HDL particles contain mostly A-I and A-II proteins.
Density of LDL:1.019- 1.063. It is relatively less dense than HDL Density of HDL is: 1.063-1.210. It is relatively denser than LDL
They deliver cholesterol to tissue They deliver cholesterol from blood and deposit to liver
Higher amounts of LDL leaves cholesterol to artery walls causing atherosclerosis

 

Higher amounts of HDL is important as it lowers the risk of cardiovascular disease
LDL particles are considered to be more pro-atherogenic HDL are be anti-atherogenic
 LDL particles are more susceptible to oxidation HDL particles have anti-oxidant, anti-inflammatory, anti-thrombotic, and anti-apoptotic properties
To help lower LDL levels:

  • Avoid foods high in saturated fat, dietary cholesterol, and excess calories in general
  • Increase exercise and physical activity
  • Maintain a healthy weight
HDL should be as high as possible. It is often possible to raise HDL by:

  • Avoiding saturated fat intake
  • Exercising for at least 20 minutes 3 times a week
  • Decreasing body weight

References and for more information:

https://www.health.harvard.edu/heart-health/how-its-made-cholesterol-production-in-your-body

https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/cholesterol

https://heartuk.org.uk/health-and-high-cholesterol

https://www.healthdirect.gov.au/what-is-cholesterol

https://www.cdc.gov/cholesterol/ldl_hdl.htm

https://www.raydel.com.au/cholesterol-difference-hdl-ldl/

https://www.healthline.com/health/hdl-vs-ldl-cholesterol#diagnosis

https://www.ncbi.nlm.nih.gov/books/NBK351/

https://www.stanfordchildrens.org/en/topic/default?id=cholesterol-ldl-hdl-and-triglycerides-in-children-and-adolescents-90-P01593

https://www.ncbi.nlm.nih.gov/books/NBK305896/

https://healthyeating.sfgate.com/ldl-hdl-differ-structurally-functionally-2003.html

https://www.healthline.com/health/hdl-vs-ldl-cholesterol#hdl-vs-ldl

https://www.medicinenet.com/hdl_vs_ldl_cholesterol_differences/article.htm#what_do_the_hdl_and_ldl_numbers_mean

 

 

 

About Kusum Wagle 216 Articles
Hello and greetings everyone! I am Kusum Wagle, MPH, WHO-TDR Scholar, BRAC James P. Grant School of Public Health, Bangladesh. I have gained profound experiences in public health sector under different thematic areas of health, nutrition, sexual and reproductive health, maternal and newborn health, research etc., targeting diverse audience of different age groups. I have performed diverse roles ranging from lecturer in the public health department of colleges, nutrition coordinator, research coordinator and consultant, in different programs, projects and academic institutions of Nepal. I also hold immense experience in working closely and persistently with government organizations, non-government organizations, UN agencies, CSOs and other stakeholders at the national and sub-national level. I have successfully led and coordinated different projects involving multi-sector participation and engagement. Moreover, I am also regularly involved in the development of different national health related programs and its guidelines.